By analyzing a gedanken experiment designed to measure the distance l between two spatially separated points, we find that this distance cannot be measured with uncertainty less than (ll 2 P) 1/3 , considerably larger than the Planck scale lP (or the string scale in string theories), the conventional-wisdom uncertainty in distance measurements. This limitation to space-time measurements is interpreted as resulting from quantum fluctuations of space-time itself. Thus, at very short distance scales, space-time is “foamy.” This intrinsic foaminess of (...) space-time provides another source of noise in the interferometers. The LIGO/VIRGO and LISA generations of gravity-wave interferometers, through future refinements, are expected to reach displacement noise levels low enough to test our proposed degree of foaminess in the structure of space-time. (shrink)

Adaptation to climate change impacts is a key research topic in business ethics that poses substantial implications on the good lives of human beings. The commercial port sector is a highly relevant study focus with its pivotal roles in supply chains and international trade. Hence, it is important to investigate whether the port planning system and practice is appropriate in tackling climate change impacts. But beforehand, we must thoroughly understand the attitude and behaviors of port planners and operators on ports’ (...) climate adaptation planning. Through a survey towards 21 ports in Canada, the paper investigates the attitude and behaviors of port planners and operators on ports’ climate adaptation planning. Towards the end, we propose a new approach so as to enable port stakeholders to carry out climate adaptation planning effectively. The paper offers important insight to researchers to investigate the ways in developing effective climate adaptation plans and practice for ports and other business sectors. (shrink)

Stress is one of the most powerful experiences to influence health and disease. Through epigenetic mechanisms, stress may generate a footprint that propagates to subsequent generations. Programming by prenatal stress or adverse experience in parents, grandparents, or earlier generations may thus be a critical determinant of lifetime health trajectories. Changes in regulation of microRNAs (miRNAs) by stress may enhance the vulnerability to certain pathogenic factors. This review explores the hypothesis that miRNAs represent stress‐responsive elements in epigenetic regulation that are potentially (...) heritable. Recent findings suggest that miRNAs are key players linking adverse early environments or ancestral stress with disease risk, thus they represent useful predictive disease biomarkers. Since miRNA signatures of disease are potentially heritable, big data management platforms will be vital to harness multi‐generational information and capture succinct yet potent biomarkers capable of directing preventative treatments. This feature would offer a unique window of opportunity to advance personalized medicine. (shrink)

Ng and singer derive the principle of utility from the fact of finite sensibility and another principle, weak majority preference: "for a community of n individuals choosing between two possibilities, x and y, if no individual prefers y to x, and at least n/2 individuals prefer x to y, then x increases social welfare and is preferable." this derivation is regarded as incorrect in a comment. this reply explains why the derivation is valid and shows that the comment is based (...) on confusing a general social ordering with a utilitarian one. (shrink)

This paper draws on the economics of ethical compliance model to examine the association between ethical reasoning, perceived risk of detection, perceived levels of penalties and Chinese auditors'' ethical behavior in an audit conflict situation. Using 53 Chinese auditors from Shenzen as subjects, and a survey questionnaire, this study found that there is a significant negative association between ethical reasoning and the likelihood of unethical behavior and that this negative association is weaker for auditors who perceive higher risks of detection.

IntroductionThe COVID-19 pandemic has led to unprecedented strain to healthcare systems worldwide and posed unique challenges to the healthcare professionals and the general public.ObjectivesThe aim of this study is to evaluate the impact of COVID-19 on the mental health, behavioral, and physical wellbeing of HCPs in the early and mid-term periods of the pandemic in comparison to non-HCPs. Thus, facilitating and guiding optimum planning and delivery of support to HCPs.Methods and AnalysisAn observational cross-sectional survey and cohort study aiming to enroll (...) over 1050 participants. Study questionnaires will be completed at baseline and after 6-weeks and 4-months. Recruitment initiated July 2020. The study was designed in London, United Kingdom, but open to participants worldwide. Baseline: Questionnaires comprising of validated self-administered screening tools for depression, anxiety, sleep-related issues, wellbeing, and burnout. The questionnaires also explore changes in behavior and physical wellbeing of the participants. In addition, associations of these mental health and behavioral factors with work-related factors and support will be explored. Six-weeks and 4-months follow-up: Follow-up questionnaires will assess change in symptoms of anxiety and depression, sleep disorders, use of alcohol and other substances, behavioral or interpersonal relationship changes. Physical wellbeing will be assessed through the presence of suspected or confirmed COVID-19 infection and absence from work. We will also evaluate the impact of variable provision of personal protection equipment, extended working hours, and concern for the wellbeing of family members, anxiety levels, and evidence of burnout.Statistical ConsiderationsThe study has 80% power to detect a 10% difference of combined depression and/or anxiety symptoms between the groups using two-sided type 1 error at 0.05 at baseline. Assuming that only 50% of these HCPs agree to be a part of a cohort survey, we will have 80% power to detect around 12% difference in the two groups in reported physical symptoms, or prevalence of depression and/or anxiety at the end of the study.EthicsThe study was approved by the Cambridge East, Research Ethics Committee.Trial Registration NumberClinicalTrials.gov, NCT04433260. (shrink)

The structure of Au layers deposited by sputtering on oxidized p-type Si substrates is investigated by a combination of scanning electron microscopy and scanning probe microscopy. The effect of the temperature on the grain structure of the layers has been determined, revealing that an annealing temperature of 300° C results in a larger grain size and smoother surfaces but generates some cracks in the film surface. At an annealing temperature of 500° C, further grain growth is observed, but a high (...) density of cracks and voids also results while there is little enhancement regarding the smoothness of the grain surfaces. (shrink)

Advancements in novel neurotechnologies, such as brain computer interfaces and neuromodulatory devices such as deep brain stimulators, will have profound implications for society and human rights. While these technologies are improving the diagnosis and treatment of mental and neurological diseases, they can also alter individual agency and estrange those using neurotechnologies from their sense of self, challenging basic notions of what it means to be human. As an international coalition of interdisciplinary scholars and practitioners, we examine these challenges and make (...) recommendations to mitigate negative consequences that could arise from the unregulated development or application of novel neurotechnologies. We explore potential ethical challenges in four key areas: identity and agency, privacy, bias, and enhancement. To address them, we propose democratic and inclusive summits to establish globally-coordinated ethical and societal guidelines for neurotechnology development and application, new measures, including “Neurorights,” for data privacy, security, and consent to empower neurotechnology users’ control over their data, new methods of identifying and preventing bias, and the adoption of public guidelines for safe and equitable distribution of neurotechnological devices. (shrink)

Contemporary bioethics education has been developed predominately within Euro-American contexts, and now, other global regions are increasingly joining the field, leading to a richer global understanding. Nevertheless, many standard bioethics curriculum materials retain a narrow geographic focus. The purpose of this article is to use local cases from the Asia-Pacific region as examples for exploring questions such as ‘what makes a case or example truly local, and why?’, ‘what topics have we found to be best explained through local cases or (...) examples?’, and ‘how does one identify a relevant local case?’ Furthermore, we consider the global application of local cases to help extend the possible scope of the discussion, opening new avenues for the development of practical bioethics educational materials. We begin with a background description and discussion of why local cases enhance bioethics education, move to an overview of what is currently available and what is not for the region, and then outline a discussion of what it means to be local using example cases drawn from Hong Kong, Australia, Pakistan, and Malaysia. We are not creating a casebook but rather constructing by example a toolbox for designing active and dynamic learning cases using regional diversity as contextualised cases with generalised principles. (shrink)

Adaptation to climate change impacts is a key research topic in business ethics that poses substantial implications on the good lives of human beings. The commercial port sector is a highly relevant study focus with its pivotal roles in supply chains and international trade. Hence, it is important to investigate whether the port planning system and practice is appropriate in tackling climate change impacts. But beforehand, we must thoroughly understand the attitude and behaviors of port planners and operators on ports’ (...) climate adaptation planning. Through a survey towards 21 ports in Canada, the paper investigates the attitude and behaviors of port planners and operators on ports’ climate adaptation planning. Towards the end, we propose a new approach so as to enable port stakeholders to carry out climate adaptation planning effectively. The paper offers important insight to researchers to investigate the ways in developing effective climate adaptation plans and practice for ports and other business sectors. (shrink)

The purpose of this research is to investigate the effectiveness of Digital Content Marketing on a Mixed Reality training platform environment with the consideration of online purchase intention through social media. E-commerce today encounters several common issues that cause customers to have reservations to purchase online. With the absence of physical contact points, customers often perceive more risks when making purchase decisions. Furthermore, online retailers often find it hard to engage customers and develop long-term relationships. In this research, a Structural (...) Equation Model is proposed to examine the efficacy of DCM from both immediate and long-term OPI. The results examine whether adopting DCM on an MR training platform environment through social media brings positive results in OPI. Empirical research was carried out through online questionnaires collected in 2021 and 2022. A total of 374 questionnaires were qualified for data analysis in this study, conducted with IBM SPSS and AMOS. The results imply that DCM is critical to stimulating both immediate and long-term OPI. The immediate OPI is positively affected by increasing perceived value through MR in DCM. Regarding the long-term OPI, increased customer engagement with DCM under MR environment can cultivate brand trust and significantly affect the long-term OPI. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

Contributors: Steven Barbone, Laurent Bove, Edwin Curley, Valérie Debuiche, Michael Della Rocca, Simon B. Duffy, Daniel Garber, Pascale Gillot, Céline Hervet, Jonathan Israel, Chantal Jaquet, Mogens Lærke, Jacqueline Lagrée, Martin Lin, Yitzhak Y. Melamed, Pierre-François Moreau, Steven Nadler, Knox Peden, Alison Peterman, Charles Ramond, Michael A. Rosenthal, Pascal Sévérac, Hasana Sharp, Jack Stetter, Ariel Suhamy, Lorenzo Vinciguerra.

Jack Reynolds has written Merleau-Ponty and Derrida, coedited Understanding Derrida, taught at the Central Institute of Higher Tibetan Studies, and shaken hands with HHDL. He remains in the realm of samsara.

In this paper, I inspect the grounds for the mature Spinozist argument for substance monism. The argument is succinctly stated at Ethics Part 1, Proposition 14. The argument appeals to two explicit premises: (1) that there must be a substance with all attributes; (2) that substances cannot share their attributes. In conjunction with a third implicit premise, that a substance cannot not have any attribute whatsoever, Spinoza infers that there can be no more than one substance. I begin the inspection (...) with the analysis of the first premise, which is provided in the form of the four proofs of God’s existence in Ethics Part 1, Proposition 11. While demonstrating how Spinoza adopts a progressive approach, where the fourth proof of God’s existence is more successful and persuasive than the third, which is more successful than the second, etc., I also unpack concepts central to Spinoza’s thinking here, including the concepts of reason (ratio) and power (potesta or potentia). I then analyze the second premise of the Spinozist argument for substance monism, as established by Ethics Part 1, Proposition 4 in conjunction with Ethics Part 1, Proposition 5. I take up and respond to the objection attributed to Leibniz that a substance p can have the attributes x and y and a substance q can have the attributes y and z, and thus that substances can share some attributes while remaining distinct. Throughout the study, my attention is focused on the argumentative procedures Spinoza adopts. This yields a close, internalist reading of the text where Spinoza effectively embraces substance monism. In conclusion to this study, I underscore to the originality of Spinoza’s argument for seventeenth century theories of substance. (shrink)

tập 1. Tư tưởng bình dân Việt Nam -- tập 2. Thời Băc thuộc và thời Đinh Lê, từ thế kỷ II trước CN dến thế kỷ X -- tập 3. Thời Lý -- tập 4. Tư tưởng Việt Nam thời Trần, 1225-1400 -- tập 5. Tư tưởng Việt Nam thời Hồ, 1380-1407 -- tập 6 & 7. Nguyễn Trãi với khủng hoảng ý thức hệ Lê-Nguyễn, 1380-1442.

Maurice Merleau-Ponty’s work is commonly associated with the philosophical movement called existentialism and its intention to begin with an analysis of the concrete experiences, perceptions, and difficulties, of human existence. However, he never propounded quite the same extreme accounts of radical freedom, being-towards-death, anguished responsibility, and conflicting relations with others, for which existentialism became both famous and notorious in the 1940s and 1950s. Perhaps because of this, he did not initially receive the same amount of attention as his French contemporaries (...) and friends, Jean-Paul Sartre and Simone de Beauvoir. These days though, his phenomenological analyses are arguably being given more attention than either, in both France and in the Anglo-American context, because they retain an ongoing relevance in fields as diverse as cognitive science, medical ethics, ecology, sociology and psychology. Although it is difficult to summarize Merleau-Ponty’s work into neat propositions, we can say that he sought to develop a radical re-description of embodied experience (with a primacy given to studies of perception), and argued that these phenomena could not be suitably understood b y the philosophical tradition because of its tendency to drift between two flawed and equally unsatisfactory alternatives: empiricism and, what he called, intellectualism. This article will seek to explain his understanding of perception, bodily movement, habit, ambiguity, and relations with others, as they were expressed in his key early work, Phenomenology of Perception, before exploring the enigmatic ontology of the chiasm and the flesh that is so evocatively described in his unfinished book, The Visible and the Invisible. (shrink)

tập 1. Trung Hoa, thời kỳ khởi điểm của triết học (thời đại Tây Chu và Đông Chu) --tạp 2. Trung Hoa, thời kỳ hoàn thành của triết học (từ Chiến Quốc đến tiền Hán) -- tập 3. Ấn Độ, Từ Phật Đà tới Phật nguyên thủy -- tập 4. Từ năm 241 trước công nguyên đến năm 907 sau công nguyên -- tập 5. Triết học Trung Hoa cận đại.

En este capítulo, defendemos la tesis de que ciertas injusticias epistémicas relacionadas al testimonio que afectan a las personas privadas de la libertad están en tensión con la deliberación democrática. En la primera sección, ofrecemos una breve discusión de la noción de la deliberación democrática. En la segunda sección, presentamos cuatro variedades de injusticia epistémica relacionadas al testimonio. En la tercera sección, consideramos algunos casos de estas variedades de injusticia epistémica en el sistema carcelario a modo ilustrativo y explicaremos cómo (...) esto crea una tensión con la deliberación democrática. (shrink)

tập 1. Cơ sở triết học của nhận thức trực quan.

Nous cherchons ici à étudier la signification du fait qu’un État, chez Spinoza, peut se comprendre intégralement comme étant une « âme » singulière. Nous montrons en quoi cette compréhension de l’État comme « âme » permet d’expliciter les éléments centraux de la théorie de l’obéissance chez Spinoza, et en quoi le succès du projet politique spinoziste n’est envisageable que de cette perspective. Nous soulevons en conclusion un paradoxe : Spinoza écrit (TP 3/8) que nul ne cède de sa faculté (...) de juger ; et à force de tirer sur ce fil, nous montrons que Spinoza y aborde de façon discrète et indirecte la possibilité de la disparition de l’État, dans la mesure même où il aura réussi à encourager l’obéissance et à faire en sorte que « l’âme » de tous devienne un bien commun. (shrink)

Résumé (FR) : L'adhésion de Spinoza à la doctrine du monisme de la substance constitue le fondement de sa philosophie. Cependant, la manière dont nous pouvons comprendre cette doctrine est loin d'être évidente. Les problèmes dans son interprétation comprennent la difficulté à caractériser le rapport entre la substance et ses modes, la validité de l’argument spinoziste pour établir le monisme, et la cohérence de maintenir qu’il peut y avoir des idées fausses alors que toute idée est en Dieu. Nous soutenons (...) ici que l’examen du contexte philosophique de l’élaboration du monisme de la substance et l’examen des contextes philosophiques entourant la réception du monisme de Spinoza, particulièrement en langue anglaise, fournissent des ressources importantes pour résoudre les difficultés susmentionnées. En effet, la réception de Spinoza en langue anglaise a été très peu étudiée jusqu’à présent. Or la réception de Spinoza en langue anglaise passe principalement par les controverses qui entourent la doctrine du monisme de la substance. Nous commençons en analysant la notion de substance dans le cadre aristotélicien, et nous montrons comment le pluralisme des substances a été progressivement fragilisé avant Spinoza. Après avoir ensuite inspecté l'argument spinoziste pour le monisme, nous analysons des interprétations du monisme avancées par ses premiers commentateurs, tels que F. Lamy. Par la suite, nous développons une historiographie inédite de la réception de Spinoza en langue anglaise et nous mettons en évidence les ressources fournies par ses commentateurs anglophones pour résoudre des difficultés interprétatives dans la théorie spinoziste du monisme de la substance. (shrink)

Este ensayo plantea una cuestión filosófica perseguida como investigación histórica que desemboca en una explicación sociológica en torno a la medición de la ciencia. Medir, etimológicamente relacionado con una praecisio adquiere su sentido más profundo en una era postontológica para describir las implicaciones culturales de un mundo privado de metafísica. Basado en un relato sucinto del surgimiento del pensamiento bibliométrico enmarcado por el debate historiográfico de principios del siglo XX entre historiadores seriales e historiadores del evento, este ensayo une tanto (...) el significado postontológico como la evidencia histórica en un análisis sociológico de la ciencia y políticas tecnológicas en la Colombia del cambio de siglo que conlleva una transformaciónradical de la universidad como institución social, del estatus del conocimiento en la sociedad contemporánea y de la identidad de nosotros los académicos que habitamos ese espacio. (shrink)

We study the relative complexity of equivalence relations and preorders from computability theory and complexity theory. Given binary relationsR,S, a componentwise reducibility is defined byR≤S⇔ ∃f∀x, y[x R y↔fS f].Here,fis taken from a suitable class of effective functions. For us the relations will be on natural numbers, andfmust be computable. We show that there is a${\rm{\Pi }}_1^0$-complete equivalence relation, but no${\rm{\Pi }}_k^0$-complete fork≥ 2. We show that${\rm{\Sigma }}_k^0$preorders arising naturally in the above-mentioned areas are${\rm{\Sigma }}_k^0$-complete. This includes polynomial timem-reducibility on (...) exponential time sets, which is${\rm{\Sigma }}_2^0$, almost inclusion on r.e. sets, which is${\rm{\Sigma }}_3^0$, and Turing reducibility on r.e. sets, which is${\rm{\Sigma }}_4^0$. (shrink)

In Mental Acts Professor Peter Geach asserts that “‘The same’ is a fragmentary expression, and has no significance unless we say or mean ‘the same X’, where ‘X’ represents a general term … ” In Reference and Generality Geach interjects the following note: “I maintain that it makes no sense to judge whether x and y are ‘the same’, or whether x remains ‘the same’, unless we add or understand some general term ‘the same F’.” Here, as in Mental Acts, (...) he goes on to say that not any general term will serve to complete ‘the same’ constructions; only substantival terms will suffice for this purpose. Finally, in his article, “ldentity,” Geach asserts that “When one says ‘x is identical with y’, this … is an incomplete expression; it is short for ‘x is the same A as y’, where ‘A’ represents some count noun understood from the context of utterance—or else, it is just a vague expression of a half-formed thought.” (We should not, incidently, conclude from this last remark that Geach thinks all and only count nouns are substantival terms. (shrink)

Building a tolerant society as the foundation for a competitive society.